A single dose with all the potency and efficacy of a good antibiotic.

  • 10, 100 and 250 ml
Quali-Quantitative Formula:

Every 100 ml of Tilcosan contains:

  • Tilmicosin (as phosphate): 30 g
  • Excipients q.s.f.: 100 ml

It is indicated for the treatment of respiratory diseases of young bovines (calves or stirks), as preventive treatment before transportation to avoid shipping fever caused by Mannhemia haemolytica (Pasteurella haemolytica) with a dose of 10 mg/kg by subcutaneous route, for the treatment of foot rot (infectious pododermatitis), of infectious bovine keratoconjunctivitis, of bovine mastitis in the dry period, with an intramammary administration at a dose of 10 ml per quarter.


Pneumonia: (10 mg/kg) 1 ml of TILCOSAN every 30 kg of weight.
Keratoconjunctivitis and foot rot: (5 to 10 mg/kg) 1 ml of Tilcosan every 30 to 60 kg of weight, according to the severity of the case and veterinary judgement.

Duration of Treatment

The treatment consists of a single application.

Method of Administration

Bovines: by intramuscular or subcutaneous route.>
Equines, swine, ovines and caprines: by intramuscular route only.


Immediate, potent and effective action on keratoconjunctivitis, respiratory diseases and foot rot.

Antibiotic, bacteriostatic agent. TILCOSAN is a wide spectrum antibiotic (tilmicosin). It is a macrolide antibiotic, synthesized from tylosin, and developed for use in veterinary medicine only. It shows good activity against Gram-positive microorganisms, with significant activity against certain Gram-negative bacteria and mycoplasmas. Tilmicosin, like other macrolides, is a bacteriostatic agent, although at high doses it can act as a bactericidal agent. The pharmacokinetic profile is characterized by low plasma concentrations and high tissue concentrations. Being a weak base (phosphate), it concentrates in tissues with low pH (generally, tissues have a lower pH than plasma). Pathologically affected tissues (e.g., lung, mammary glands, foot rot) tend to lower their pH further, which creates an ideal environment for a higher concentration of tilmicosin in those affected tissues. Besides, tilmicosin has a strong penetration in macrophages, it is stored in lysosomes, and in this site, it affects the microorganisms that are phagocytosed; thus the synthesis of proteins being inhibited.